On November 7, the 2024 Oriental Beauty Valley International Cosmetics Conference, themed "Technology and Innovation Leading the Beauty of the Future," was held in Shanghai. Chen Juanling, General Manager of Public Affairs at CHANDO Group, attended the opening ceremony and delivered a keynote speech titled Technology and Innovation: Born for Beauty as a representative of national brands.

Image: Chen Juanling, General Manager of Public Affairs at CHANDO Group, delivers a speech

Strengthening Raw Material Technology to Fuel Innovation in Product Development

As a digitally-driven technology cosmetics enterprise, CHANDO Group has consistently adhered to dual engines of product technology and digital technology to drive its sustainable development.

Rooted in independent R&D and global collaboration, the Group has established six scientific research platforms: Consumer Big Data Insights, Eastern Skin Research, Raw Material Screening and Development, Formulation Technology, Packaging Development, and Six Senses and Six Standards Evaluation. Backed by a top-tier R&D team led by hundreds of professionals and multidisciplinary experts worldwide, CHANDO Group has solidified its foundation for iterative product innovation.

Image: CHANDO Group R&D Center

Leveraging robust scientific capabilities, CHANDO Group continues to advance the core of product technology: raw material innovation. Utilizing technologies such as microbial fermentation and plant stem cell culture, the Group has independently developed key cosmetic ingredients, including HiMurchaSin, BlueTech Snow, and Rosa gracilis Cell Clusters.

Among these, the breakthrough of HiMurchaSin®, derived from polar yeast, marks a comprehensive advancement from strain selection and fermentation process optimization to product application. This innovation reduces China’s reliance on imported cosmetic ingredients and establishes technological barriers for the domestic industry.

During the development of HiMurchaSin®, the R&D team overcame instability in fermentation processes by pioneering the fifth-generation intelligent fermentation technology. Coupled with low-temperature, preservative-free downstream processing, this method maximizes the enrichment of active components.

Scientific validation through 2D/3D skin cell models and human clinical trials confirms HiMurchaSin®’s safety and efficacy. Its powerful reparative and cellular regenerative capabilities inject fresh technological vitality into the global beauty market.

This year, in collaboration with the Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, CHANDO Group conducted a systematic analysis of quantitative big data on facial skin aging from over 300,000 women across 32 Chinese provinces. The study revealed statistically significant evidence supporting a trend of delayed skin aging among Chinese women and introduced the pioneering concept of “fatigue-induced aging.”

Building on years of self-developed research on Eastern skin anti-aging targets and the breakthrough upgrade of HiMurchaSin®, CHANDO Group pioneered “anti-fatigue aging” technology—HiMurchaSin® Fermentation Filtrate & Lysate—setting a new benchmark for domestic raw materials.

Image: Research Project on Characteristics and Mechanisms of Skin Rejuvenation in Chinese Women

HiMurchaSin® Fermentation Filtrate and Lysate are enriched with 940 active small molecular components and 7 major categories of nutrients, targeting the skin’s basal layer to precisely counteract key pathways of fatigue-induced aging.

Flavonoids neutralize free radicals, adenosine derivatives replenish cellular energy, and nucleosides stimulate cell renewal. Together, they awaken the skin’s regenerative vitality, achieving 8x cellular renewal and a 362% increase in collagen self-renewal.HiMurchaSin® Lysate, processed through a unique fermentation technology, achieves higher enrichment of key active components. Combined with its strong permeability and absorption capabilities, it penetrates directly to the skin’s basal layer to combat fatigue-induced aging.

The sixth generation of CHANDO REJUVENATION REPAIRING ESSENCE  marks the first application of anti-fatigue aging research in skincare. It addresses current anti-aging demands in China, fills industry gaps, and demonstrates groundbreaking leadership in the anti-aging market.

Image: CHANDO REJUVENATION REPAIRING ESSENCE (6th Generation)

In August of this year, HiMurchaSin® yeast returned to Earth after a 154-day space voyage aboard the Shenzhou-16 spacecraft, completing the strain handover. CHANDO Group and the State Key Laboratory of Microbial Metabolism at Shanghai Jiao Tong University jointly announced a research initiative on space yeast HiMurchaSin®, propelling anti-fatigue aging yeast skincare technology into the space era.

Additionally, for Himalayan botanical development, CHANDO Group draws insights from traditional Tibetan medicinal classics and intangible cultural heritage. Guided by sustainable principles, the Group integrates modern technological innovations to create consumer-centric products.

By selecting ingredients from Tibetan medical texts, CHANDO developed a proprietary scalp care complex—Five Herbal Elixir. This formula revitalizes the scalp through multi-dimensional benefits: detoxification, circulation enhancement, and repair. It debuted in CHANDO’s Scalp Care Series in 2022.

Image: CHANDO New Herbal Hair Care Series 

Pioneering Cutting-Edge Technology: Breakthroughs in microRNA Research

The 2024 Nobel Prize in Physiology or Medicine was awarded to Professor Victor Ambros of the University of Massachusetts Medical School and Professor Gary Ruvkun of Harvard Medical School for their discoveries in microRNA and its role in post-transcriptional gene regulation.

As early as 2014, CHANDO Group initiated a Sino-French joint research project with Ashland Group. By analyzing skin samples across ages and environmental exposures, the project identified endogenous aging-related microRNAs and exogenous aging-related microRNAs.

From big data analysis, 16 skin-specific microRNAs linked to aging, photoaging, air pollution, and East-West ethnic differences were identified. Bioinformatics further revealed 15 skin-related targets.

Subsequently, CHANDO Group screened over 800 Himalayan plants and discovered that plant-derived microRNAs regulate skin aging-related microRNAs in Eastern populations. Preliminary evidence confirmed cross-kingdom regulation of skin miRNAs by Usnea barbata extract. To date, 6 invention patents have been authorized.

In 2021, CHANDO Group translated this discovery into Epigenetic Dermal Repair Technology, applied in the CHANDO Gold Diamond Micro-Sculpting Series.

Featuring Himalayan Usnea barbata Extract, Triple Renewal Peptides, and Mechanical Firming Factors, third-party tests show that the series enhances elasticity, reduces gravity lines, and reshapes skin tension for a 4D micro-sculpted contour. After 28 days of use, jawline firmness improves by 13.55%, and nasolabial folds diminish by 13.69%.

Image: CHANDO Gold Diamond Series

CHANDO Group’s forward-looking microRNA research has yielded foundational insights and market-ready applications, addressing differentiated anti-aging needs of Chinese consumers. This Nobel-recognized cutting-edge technology exemplifies the Group’s scientific excellence.

Enhancing Beauty Industry Productivity and Building Green Cosmetics

Building green cosmetics hinges on advancing productivity through innovation. As Chen Juanling stated: “New productive forces are innovation-led, particularly driven by technological breakthroughs.

For CHANDO Group, beyond product technology, digital innovation is another pillar. Since initiating digital transformation in 2020, the Group has deployed 105 systems, integrating digitization across R&D, production, logistics, marketing, and management.Digital revenue, digital retail, and digital assets all rank far ahead of industry benchmarks.

Through continuous technological innovation, CHANDO Group comprehensively empowers its green cosmetics initiative. Beyond building dual technological engines, following Chairman Zheng Chunying’s vision for green cosmetics presented at last year’s international cosmetics conference, the Group officially launched its 2030 Sustainability Strategy this year. Aligned with the UN’s 17 Sustainable Development Goals (SDGs), the strategy establishes 12 sustainability targets across environmental, social, and governance (ESG) aspects. By integrating these goals into business practices, CHANDO Group is developing, refining, and optimizing a carbon management system. Green technologies are embedded throughout the product’s full lifecycle to drive high-quality development of green cosmetics, ultimately striving for harmonious coexistence between nature and beauty.

Chen Juanling concluded: “Moving forward, CHANDO Group will continue to innovate in beauty technology, delivering products of unparalleled value for global consumers’ beauty and health. We aim to propel industry growth and co-create a beautiful China and world.”