Amid the rising popularity of skincare concepts such as "efficacy-driven skincare" and "microbiome skincare," consumers are increasingly aware of cosmetic ingredients and demand higher efficacy and safety. Fermentation skincare, a subcategory of microbiome skincare, is gaining momentum in China due to its dual advantages of gentleness and multifunctionality.
In response to the proliferation of "fermentation filtrates" and "yeast lysates" in the market, CHANDO, China’s leading domestic brand, has forged a new path. Recently, CHANDO collaborated with renowned dermatologist Dr. Liu Wei and the research platform Basic Skincare Insights to pioneer the concept of "fatigue-induced aging." Addressing this phenomenon, CHANDO launched the sixth-generation REJUVENATION REPAIRING ESSENCE (Little Purple Bottle). Breakthroughs in HiMurchaSin™ fermentation filtrate and lysate technology empower this new generation with 8x cellular-level rejuvenation, creating a true yeast essence tailored to combat fatigue-induced aging for Chinese consumers. This innovation elevates CHANDO’s leadership in fermentation skincare across technology, ingredients, efficacy, and user experience.
CHANDO Reveals the Truth Behind Fatigue-Induced Aging: Cellular-Level Rejuvenation is Key
In recent years, trending topics like "exhaustion-induced dullness" and "late-night face" on social media highlight widespread concerns about skin issues caused by lifestyle stress. In early 2024, CHANDO partnered with OIB.CHINA and Basic Skincare Insights to conduct a nationwide survey on fatigue behaviors among Chinese consumers. The study aimed to assess awareness of fatigue-induced aging, identify key demographic traits, and explore skincare needs. The findings were compiled into the Scientific Management Guide for Fatigue-Induced Aging, released on May 1. As the industry’s first anti-aging guide on this topic, it provides comprehensive insights into the phenomenon, scientific evidence, and solutions.
Scientific research reveals a strong correlation between cellular aging and chronic stress. External stressors (e.g., UV overexposure, air pollution, noise) and internal stressors (e.g., overwork, poor diet, lack of exercise) are two major contributors to fatigue-induced aging. Accumulated stress and insufficient cellular energy exacerbate impaired cell proliferation, where cell renewal lags behind aging—a root cause requiring urgent solutions. Fatigue-induced aging is a holistic state; akin to daily exhaustion not solely from sleep deprivation, multiple stressors trigger issues like sagging, dullness, laxity, and roughness across skin layers. Thus, single-target solutions are inadequate.
In conclusion, cellular-level rejuvenation is essential to combat fatigue-induced aging. Through over a decade of research, CHANDO identified three core strategies: Cellular-Level Rejuvenation, Layered Anti-Aging, and Multi-Scenario Compatibility. This led to a revolutionary breakthrough in HiMurchaSin™, utilizing its fermentation filtrate and lysate to create a high-concentration, high-activity "true yeast" that delivers remarkable anti-aging efficacy.
Flagship Product REJUVENATION REPAIRING ESSENCE Upgraded: 8x Cellular Rejuvenation Against Fatigue-Induced Aging
HiMurchaSin™ fermentation filtrate and lysate contain 940 active small molecules that deliver targeted nutrients to the basal layer. Adenosine in the lysate constitutes 70% of the total metabolites, replenishing cellular energy and boosting renewal. Through fifth-generation fermentation technology, HiMurchaSin™ lysate achieves enhanced penetration and absorption, activating layered anti-aging across all skin layers to promote regeneration and repair.
Building on technological innovation, the sixth-generation CHANDO REJUVENATION REPAIRING ESSENCE is China’s first anti-fatigue aging serum, upgraded in efficacy, user experience, and packaging. For the first time, it incorporates HiMurchaSin™ fermentation filtrate and lysate—each drop contains 2 million yeast cell extracts, penetrating the dermis within 8 hours to activate 8x cellular rejuvenation for plump, resilient skin. Additionally, antioxidant defense is enhanced 10-fold with 99% pure ergothioneine, small-molecule carnosine, and tranexamic acid, offering sustained protection and gentle brightening. Third-party studies confirm visible repair within 1 hour and significant reduction of five major wrinkles in 28 days.
Reappearing in "The Great Chinese Ingredients," Redefining the Heights of Chinese Innovation
As CHANDO’s proprietary patented ingredient, HiMurchaSin™ epitomizes fifth-generation intelligent fermentation technology. Since 2013, CHANDO Group has collaborated with the Institute of Microbiology, Chinese Academy of Sciences, to advance microbial fermentation research. CHANDO’s R&D team traveled deep into the Himalayas, isolating 558 polar microbial strains via gene sequencing to build a unique Himalayan strain library. HiMurchaSin™, selected from these strains, is developed through dedicated fifth-generation fermentation technology. This technology excels in strain construction, validation, and industrialization, naturally enhancing active ingredient enrichment, efficacy, and safety while minimizing side effects.
Launched in 2022 as part of the "The Great Chinese Ingredients" initiative, HiMurchaSin™ garnered significant industry and consumer attention. This year, its technological breakthrough aligns with the upgraded REJUVENATION REPAIRING ESSENCE, reaffirming its status as an "Amazing Chinese Ingredient"—China’s true yeast combating true fatigue-induced aging.
The rise of Chinese ingredients reflects CHANDO’s scientific rigor and R&D strength. As a natural high-tech brand rooted in the Himalayas, CHANDO leverages the region’s rare resources to develop proprietary products, breaking international monopolies on core cosmetic ingredients and delivering high-efficacy, affordable solutions to global beauty seekers.
The sixth-generation REJUVENATION REPAIRING ESSENCE embodies CHANDO’s technological breakthroughs and marks a new frontier in anti-aging. Moving forward, CHANDO will continue prioritizing original innovation to enhance consumer experiences, support the Healthy China initiative, and redefine the potential of "Made by China."
